2011 Agenda
MONDAY, JULY 11
| 5:00 - 8:00 PM | Registration |
TUESDAY, JULY 12
| 7:30 AM | Registration Opens |
| 7:45 - 8:45 AM | Continental Breakfast in Exhibit/Poster Area |
| 8:45 - 9:00 AM | Welcome to DNA Vaccines 2011 David Weiner, PhD - Professor, University of Pennsylvania |
| 9:00 - 9:30 AM | The Future of Vaccines: Opportunities and Challenges John Shiver, PhD - Vice President, Vaccines Discovery, Merck Research Laboratories |
| 9:30 - 10:00 AM | Antibody and B Cell Responses to the HIV-1 Envelope Glycoproteins Rich Wyatt, PhD - Director of Viral Immunology, IAVI Center for Neutralizing Antibodies at TSRI, Professor of Immunolgy, The Scripps Research Institute |
| 10:00 - 10:30 AM | HIV Vaccine Development after RV 144: Lessons Learned and Future Plans Merlin Robb, MD - HJF HIV Program Director, U.S. Military HIV Research Program |
| 10:30 - 11:00 AM | Coffee/Networking Break in Exhibit/Poster Area |
Approaches to HIV Session
| 11:00 - 11:20 AM | Prime-boost Strategies for Protective Immunity Against HIV Susan Barnett, PhD - Senior Project Leader, Senior Director, Vaccine Research, Novartis Vaccines & Diagnostics |
| 11:22 - 11:44 AM | GeoVax DNA/MVA HIV Vaccine, Preclinical and Clinical Studies Harriet Robinson, PhD - Chief Scientific Officer, GeoVax, Inc. |
| 11:44 AM - 12:06 PM | DNA Priming Immunization for Antibody Responses Shan Lu, MD, PhD - Professor of Medicine, University of Massachusetts Medical School |
| 12:06 - 12:30 PM | Preclinical and Clinical Approaches to Genetic HIV Vaccines Britta Wahren, MD, PhD - Professor, Karolinska Institutet |
| 12:30 - 1:45 PM | Lunch in Exhibit/Poster Area |
DNA & EP Session
| 1:45 - 2:10 PM | DNA and Protein Vaccination Confers Protection Upon Mucosal Challenge with Heterologous SIVsmE660 in Rhesus Macaques Barbara Felber, PhD - Principal Investigator, National Cancer Institute |
| 2:10 - 2:35 PM | Expanded Clinical Testing of an Integrated Device Technology for Electroporation Mediated DNA Vaccine Delivery Drew Hannaman - Vice President, Ichor Medical Systems, Inc |
| 2:35 - 3:05 PM | Engineering DNA Approaches for HIV
David Weiner, PhD - Professor, University of Pennsylvania |
| 3:05 - 3:30 PM | Coffee/Networking Break in Exhibit/Poster Area |
Approaches to Infectious Disease Session
| 3:30 - 4:00 PM | Phase 2 Clinical Trial Results of a Therapeutic DNA Vaccine, TransVax™, for Control of Cytomegalovirus in Hematopoietic Cell Transplant Recipients Alain Rolland, PhD - Executive Vice President, Product Development, Vical Inc |
| 4:00 - 4:30 PM | New Malaria Vaccines Thomas Richie, MD, PhD - Research Coordinator, US Military Malaria Vaccine Program, Naval Medical Research Center |
| 4:30 - 5:30PM | Plenary Roundtable I - Chairs John Sterling & David Weiner Development and Commercialization of Novel Vaccines Kathrin Jansen, PhD - Senior Vice President, Vaccine Research & Early Development, Pfizer, Inc. Niranjan Sardesai, PhD - Senior Vice President, Inovio Pharmaceuticals, Inc. Alain Rolland, PhD - Executive Vice President, Product Development, Vical, Inc. Jeffrey Ulmer, PhD - Global Head, External Research, Novartis Vaccines & Diagnostics |
| 5:30 - 7:00 PM | Cocktail Reception in Exhibit/Poster Area |
WEDNESDAY, JULY 13
| 7:30 AM | Registration Opens |
Immune Mechanisms & Vaccine Session
| 7:45 - 8:45 AM | Continental Breakfast in Exhibit/Poster Area |
| 8:45 - 915 AM | Correlates of Immunity After Vaccination Stanley Plotkin, PhD - Emeritus Professor, Wistar Institute and University of Pennsylvania, Professor, Johns Hopkins Bloomberg School of Public Health, Consultant, Sanofi Pasteur & Principal of Vaxconsult |
| 9:15 - 9:40 AM | Follicular Helper CD4 T Cell Differentiation and the Development of Protective Antibody Responses Shane Crotty, PhD - Associate Professor, Vaccine Discovery, La Jolla Institute for Allergy & Immunology |
| 9:40 - 10:05 AM | Novel Approaches to T Cell Analysis in Vaccination Mike Betts, PhD - Assistant Professor, Microbiology, University of Pennsylvania |
| 10:05 - 10:30 AM | Role of Non-Human Primates in the Evaluation of Vectored Vaccine Approaches Danilo Casimiro, PhD - Director, Vaccine R&D, Merck & Co |
| 10:30 - 11:00 AM | Coffee/Networking Break in Exhibit/Poster Area |
Infectious Diseases Session
| 11:00 - 11:20 AM | DNA Vaccines Against Biodefense Threats Connie Schmaljohn, PhD - Chief Scientist, Infectious Diseases, US Army Medical Research Institute of Infectious Diseases |
| 11:25 - 11:45 AM | DNA Vaccines for Tuberculosis Thomas Evans, MD - Chief Scientific Officer, Aeras |
| 11:50 - 12:10 PM | Approaches to HCV Virus Infection Matti Sällberg, PhD - Professor, Karolinska Institutet |
| 12:10 - 12:30 PM | Vaccines for Pandemics Gary Kobinger, PhD - Chief, Special Pathogens, Public Health Agency of Canada |
| 12:30 - 4:00 PM | Break to Explore downtown Coronado Bay and/or San Diego Complimentary transportation to downtown Coronado and discounted cabs to San Diego |
New Vaccine Approaches Session
| 4:00 - 4:20 PM | New Applications of DNA Vaccines Bin Wang, PhD - Professor, Fudan University Shanghai Medical College |
| 4:20 - 4:40 PM | Improved Anti-Viral Immunity Provided by pDNA Prime/rVSV Boost Immunization Mike Egan, PhD - Director of Immunology, Profectus Biosciences |
| 4:40 - 5:00 PM | Targeting Mucosal Immunity with a DNA Vaccine Platform Michele A. Kutzler, PhD - Assistant Professor, Drexel University College of Medicine |
| 5:00 - 5:50 PM | Plenary Roundtable II - Chair Jeffrey Ulmer Vaccines for Emerging Markets Thomas G. Evans, MD - Chief Scientific Officer, Aeras Ashley J. Birkett, PhD - Director, Pre- and Early-Clinical Research and Development, PATH Malaria Vaccine Initiative (MVI) Thomas L. Richie, MD, PhD - Research Coordinator, US Military Malaria Vaccine Program, Naval Medical Research Center Stanley Plotkin, PhD - Emeritus Professor, Wistar Institute and University of Pennsylvania, Professor, Johns Hopkins Bloomberg School of Public Health, Consultant, Sanofi Pasteur & Principal of Vaxconsult Merlin L. Robb, MD - Deputy Director, Clinical Research, US Military HIV Research Program Danilo Casimiro, PhD - Director, Vaccine R&D, Merck & Co |
| 6:00 - 7:30 PM | Cocktail Reception in Exhibit/Poster Area |
| 7:30 - 10:00 PM | Gala Awards Dinner Sponsored by Inovio & VGXi Dinner Speaker: Kathrin Jansen, PhD - Senior Vice President, Vaccine Research & Early Development, Pfizer, Inc. The Hilleman and Ginsberg Awards are being generously supported by Aldevron. |
THURSDAY, JULY 14
| 7:30 AM | Registration Opens |
| 7:30 - 8:30 AM | Continental Breakfast in Exhibit/Poster Area |
Industry Session
| 8:30 - 8:45 AM | Scale-up of a Plasmid DNA Purification Process Based on PlasmidSelect Xtra for Production of GMP Grade pDNA Tony Hitchcock - Head of Manufacturing Technologies, RecipharmCobra Biologics |
| 8:45 - 9:00 AM | Scaleable and Continuous GMP Plasmid Purification Process Philippe Ledent, PhD - Process Transfer & Development Manager, Eurogentec Biologics |
| 9:00 - 9:15 AM | Commercializing DNA Vaccines: What Will the Process Look Like? A Proposed Strategy for Manufacturing and Distribution of a DNA Vaccine Rick Hancock - President, Althea Technologies |
| 9:15 - 9:30 AM | Implementation of Cleaning Validation for cGMP Manufacture of DNA Vaccines Henry Hebel - COO, Marketing, VGXI, Inc. |
Abstract Session 1
| 9:30 - 9:42 AM | Harnessing DNA-Sensing Pathways of Innate Immunity for DNA Vaccines Against Cancer Alvaro Lladser, PhD - Associate Researcher, Fundacion Ciencia para la Vida, Principal Investigator, Laboratory of Gene Immunotherapy |
| 9:42 - 9:54 AM | Development of Vaxfectin®-formulated HSV-2 Plasmid DNA Vaccines for Prophylactic and Therapeutic Applications Sean Sullivan, PhD - Executive Director, Pharmaceutical Sciences, Vical, Inc. |
| 9:54 - 10:06 AM | DNA-Based HIV Vaccines Do Not Induce Generalized T Cell Activation Within Mucosal Tissues Morgan Reuter, PhD - University of Pennsylvania |
| 10:06 - 10:18 AM | Antitumor Therapeutic Efficacy of cDNA Delivered by Electroporation in Animal Tumor Models Jeong-Im Sin, PhD - Professor of Microbiology, Kangwon National University School of Medicine |
| 10:18 - 10:30 AM | Importance of Electrode Choice on Gene Electrotransfer to Skin Julie Gehl, MD - Clinical Associate Research Professor, Copenhagen University Hospital Herlev |
| 10:30 - 11:00 AM | Coffee/Networking Break in Exhibit/Poster Area |
Cancer Session
| 11:00 - 11:30 AM | Targeting Tumors with T cells: The Normal Repertoire and Beyond Phil Greenberg, MD - Professor, Immunology and Medicine/Oncology, University of Washington and Fred Hutchinson Cancer Research Center |
| 11:30 AM - 12:00 PM | Therapeutic HPV Vaccines Cornelia Trimble, MD - Associate Professor, Gynecology & Obstetrics, Johns Hopkins University School of Medicine |
| 12:00 - 12:30 PM | Clinical Studies of DNA Vaccination Mark Bagarazzi, MD - Chief Medical Officer, Inovio Pharmaceuticals |
| 12:30 - 1:30 PM | Lunch in Exhibit/Poster Area |
Tumor Immune Therapy Session
| 1:30 - 2:00 PM | Cancer Immune Therapy Christian Ottensmeier, MD, PhD - Professor of Experimental Medicine, University of Southampton, Cancer Sciences |
| 2:00 - 2:30 PM | Immunotherapy for Cancer Facilitated by Electro Gene Transfer Richard Heller, PhD - Director and Professor, Frank Reidy Research Center for Bioelectrics |
| 2:30 - 3:00pm | Electroporative Gene Therapy with IL-12 Plasmid in Metastatic Melanoma Adil Daud, MD - Clinical Professor of Medicine, University of California, San Francisco |
| 3:00 - 3:30 PM | Coffee/Networking Break in Exhibit/Poster Area |
Abstract Session 2
| 3:30 - 3:42 PM | Malaria Infection Impacts Primate Systemic Immune Profile which leads to an Altered Vaccine Induced Immune Response Jean Boyer, PhD - Associate Research Professor, Pathology and Lab Medicine, University of Pennsylvania |
| 3:42 - 3:54 PM | Mtb32 is a Promising Tuberculosis Antigen for DNA Vaccination in Pre- and Post-exposure Mouse Models So Shin Ahn - POSTECH |
| 3:54 - 4:06 PM | Inducing Potent Immune Responses to Multiple Liver-Stage Malaria Antigens Using DNA Vaccines Bernadette Ferraro, PhD - Postdoctoral Fellow, Laboratory and Pathology Medicine University of Pennsylvania School of Medicine |
| 4:06 - 4:18 PM | A Multi-agent DNA Vaccine for Venezuelan, Eastern, and Western Equine Encephalitis Viruses Delivered by Electroporation Lesley C. Dupuy, Jr. PhD - Contract Principal Investigator, Virology Division, US Army Medical Research Institute of Infectious Diseases |
| 4:18 - 4:30 PM | Smallpox DNA Vaccine Delivered by PharmaJet Needle-Free Jet Injection & Muscle Electroporation: Immunogenicity and Protection in Rabbits (Aerosol Challenge) Jay W. Hooper, PhD - Chief, Molecular Virology Branch, Virology Division, US Army Medical Research Institute of Infectious Diseases |
| 4:30 - 4:42 PM | Contactless Magnetic Electroporation Thomas J. Kardos - President & Founder, MagneGene, Inc. |
| 4:42 PM | Closing Summary |
| 5:00 PM | Meeting Adjourns |