DNA Vaccines 2010 in New Orleans was a great success. Watch this site for updated info for dates and location of the next DNA Vaccines conference.

Hosted by Mary Ann Liebert, organized by BioConferences and Program Chair Dr. David B. Weiner, PhD. – University of Pennsylvania, USA

March 2 - 4, 2010
Sheraton New Orleans Hotel
New Orleans, LA


Final Agenda:


MARCH 2, 2010

Registration Opens: 9am - 5pm

Morning Sessions
Session Chair: John Shiver, Connie Schmaljohn

10:00 — 10:30AM
Welcome Address from the Program Chairman: Enhancing DNA Vaccine Immunity in Vivo

David B. Weiner, PhDUniversity of Pennsylvania

10:30 — 11:00AM
The Future of Vaccines from an Industry Perspective

John Shiver, PhDMerck

11:00 — 11:30AM
Human Immune Responses to Vaccination

Mark Slifka, PhDOSHU

11:30 — 12:00AM
Preclinical and Clinical Studies of DNA Vaccines for Biodefense

Connie Schmaljohn, PhDUSAMRIID

12:00 — 1:10PM Lunch Opens

Afternoon Session 1

Session Chairs: Iacob Matheson, Shan Lu

1:10 — 1:30PM
Live Attenuated Influenza Vaccine for Seasonal and Pandemic Applications

Hong JinMedimmune

1:30 — 1:50PM
The Strengths and Weaknesses of Inducing Mismatched Immunity to Expand Cross-Protection Against Influenza Viruses

Gary Kobinger, PhDPHAC

1:50 — 2:10PM
Approaches to Influenza

Jukka Hartikka, PhDVical

2:10 — 2:30PM
SynCon™ DNA Vaccines for Infectious Diseases

NiranJan Sardesai, PhDInovio Biomedical Corporation

2:30 — 3:00PM
Approaches to HCV DNA Vaccines

Matti Sällberg, PhDTripep Pharma

3:00 — 3:30PM Break

Afternoon Session 2

Session Chairs: T.C. Wu, Gary Kobinger

3:30 — 3:50PM
Immunogenicity of VRC DNA Vaccines for HIV, WNV and Influenza

Julie LedgerwoodVRC

3:50 — 4:10PM
T Cell Responses in Prostate Cancer Patients Immunized with Xenogeneic and Syngeneic PSMA DNA Vaccines

Polly Gregor, PhDMSKCC

4:10 — 4:30PM
Therapeutic HPV DNA Vaccine Development

T.C. Wu, MD, PhDThe Johns Hopkins Medical Institutions

4:30 — 4:45PM
The PEDVAC Trial: Preliminary Safety Data from the First Therapeutic DNA Vaccination in HIV-Infected Children

Britta Wahren, MD, PhDKarolinska Institute

4:45 — 5:00PM
Immunization with Drug-Resistant HIV-1 Enzyme Genes

Maria IsaguliantsKarolinska Institute

5:00 — 7:30PM Cocktail Social Hour in Exhibits Poster Area

MARCH 3, 2010

8:00 — 9:00AM Breakfast

Morning Session 1

Session Chairs: Mark Bagarazzi, Jeffrey Ulmer

9:00 — 9:30AM
RV 144 ALVAC-HIV/AIDSVAX Study: Implications for HIV Vaccine Development

Col. Nelson Michael, MD, PhDWalter Reed Army Institute of Research, US Military HIV Research Program (MHRP)

9:30 — 10:00AM
Technologies for Improved Vaccines
Jeffrey Ulmer, PhDNovartis Vaccines & Diagnostics

10:00 — 10:30AM
Mucosal Immunology of SIV Infection

Ron Veazey, DVM, PhDTulane University

10:30 — 11:00AM Break

Morning Session 2

Session Chairs: Jim Mullins, Harriet Robinson

11:00 — 11:20AM
What is a Protective T Cell Response

Michael Betts, PhDUniversity of Pennsylvania School of Medicine

11:20 — 11:40AM
Heterologous Prime-Boost HIV Vaccines

Shan Lu, MD, PhDUniversity of Massachusetts Medical School

11:40 — 12:00PM
Studies in Preclinical Macaque Models of DNA/MVA Vaccines

Harriet L. Robinson, PhDGeovax Inc.

12:00 — 1:10PM Lunch Break

Afternoon Session 1

Session Chairs: George Pavlakis, Susan Zolla-Pazner

1:10 — 1:30PM
Clinical Experiences of HIV Genetic Vaccines

Britta Wahren, MD, PhDKarolinska Institute

1:30 — 1:50PM
Optimization of DNA and Combination Vaccines in Macaques

George Pavlakis, MD, PhDNCI

1:50 — 2:10PM
Induction of Cross-clade Neutralizing Antibodies with a Prime/Boost Vaccine Strategy Focused on a Neutralizing Epitope

Susan Zolla-Pazner, PhDNYU Medical School

2:10 — 2:30PM
In Vivo Electroporation Enhances the Immunogenicity of ADVAX, a DNA-based HIV-1 Vaccine Candidate, in Healthy Volunteers

Sandhya Vasan, MDAaron Diamond AIDS Research Center

2:30 — 2:50PM
Genomic Signatures of DNA Vaccines

Jean Boyer, PhDUniversity of Pennsylvania

2:50 — 3:10PM Break

Afternoon Session 2

Session Chairs: Michael Betts, Matti Sallberg

3:10 — 3:30PM
Conserved Elements Vaccine for HIV-1 Gagp24 is Immunogenic in Mice and Macaques

James Mullins, PhDUniversity of Washington

3:30 — 3:45PM
Co-Delivery of Mucosal Chemokine Plasmids in a Systemically Administered DNA Vaccine Elicits Systemic and Mucosal Immune Reponses in Rhesus Macaques

Michele KutzlerDrexel University

3:45 — 4:00PM
In Vivo Intracellular Injection Needle (IvIn) Technology: A New Needle for Improved Cellular Uptake of DNA in a Live Animal

Lars FrelinKarolinska Insitute

4:00 — 4:15PM
An Adjuvanted Therapeutic DNA Vaccine Enhances Mucosal T-Cell Responses, Reduces Virus in the Gut, and Prevents Viral Rebound in Rhesus Macaques Chronically Infected with SIV

Deborah FullerAlbany Medical College

Industry Discussion Panel - Chair: David Weiner

4:15 — 5:00PM
Panel Discussion:

Stanley Plotkin, Joseph Kim, Andrew Murdin, Tim Leard, Jeffrey Ulmer

Dinner Speaker:

Special Invited Speaker: Correlates of Protection from Infection
Stanley Plotkin, MDVaxconsult LLC introduced by Andrew Murdin - Sanofi Aventis

Presentation of Maurice Hilleman Award - David Kaslow

Presentation of Richard Ginsberg Award - David Weiner

5:30 - 7:00PM Cocktail Social Hour in Exhibits Poster Area

7:00PM Gala Dinner in Banquet Hall

MARCH 4, 2010

8:00 — 9:00AM Breakfast

Morning Session 1

Session Chairs: Henry Hebel, James Williams

9:00 — 9:15AM
Developing a Successful Contact Manufacturing Organization Partnership: A Case Study

Henry HebelVGXi

9:15 — 9:30AM
DNA Vaccine Purification: Increasing Productivity and Purity of Plasmid DNA by Monolith Chromatography

Matjaz PeterkaBIA Separations

9:30 — 9:45AM
Improved Antibiotic-Free Plasmid Vector Design by Incorporation of Transient Expression Enhancers

James WilliamsNature Technology

9:45 — 10:00AM
Accelerating the Development and Commercialization of DNA Vaccines

Magda Marquet, PhDAlthea Technologies

10:00 — 10:20AM
Comparative Performance Evaluation of Electroporation Mediated DNA Immunization Versus Conventional Vaccine Approaches

Drew Hannaman, PhD Ichor Medical Systems

10:20 — 10:50AM Break

Morning Session 2

Session Chairs: Bin Wang, Ruxandra Draghia-Akli

10:50 — 11:10AM
Antigen Specific Immunity after CTLA-4 Blockade: Investigating the Role of Prior Vaccination

Jianda Yuan, MD, PhDMSKCC

11:10 — 11:30AM
Canine Melanoma Vaccine, DNA, A Review of Efficacy and Licensure

Tim Leard, DVM, PhDMerial

11:30 — 11:50AM
Tolerogenic Vaccination to Induce Antigen Specific T Regulatory Cells to Suppress Inflammatory Responses

Bin Wang, PhDChina Agricultural University

11:50 — 12:10PM
DNA Vaccine Based on Cancer-Testis Antigen, BORIS and IL21 Molecular Adjuvant in Extremely Effective For Treatment of Metastatic Disease

Michael Agadjanyan, PhDThe Institute for Molecular Medicine

12:10 — 1:20PM Lunch

Afternoon Session

Session Chair: David Kaslow, Ashley Birkett

1:20 — 1:40PM
Recent Advances in Malaria Vaccine Development

Ashley Birkett, PhDPATH MVI

1:40 — 2:00PM
Transformative Technologies in the Vaccine Area - How Will We Know?

David Kaslow, MDMerck

2:00 — 2:15PM
Structure and Biological Activity of Synthetic DNA Vaccines Formulated to Nanomedicines

Julianna Lisziewicz, PhDGenetic Immunity

2:20 — 2:35PM
Prototype Development and Pre-Clinical Immunogenicity Analysis of a Novel Minimally Invasive Electroporation Device

Kate Broderick, PhDInovio Biomedical Corporation

2:30 — 3:00PM Break

Vaccine Stakeholder Panel - Chair: Ray Spier

3:00 — 3:45PM
DNA Vaccines: A View from Both Sides of the Fence and Both Sides of the Pond

Panel Discussion - David Kaslow, Ruxandra Draghia-Akli, Ashley Birkett, Jeffrey Ulmer

3:45 — 4:00PM Closing Session Summary – Niranjan Sardesai, Britta Wahren & David Weiner